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Treatment for Fatty Infiltration of the Liver

Your liver cells normally contain a small amount of stored fat.

Nonalcoholic fatty liver disease (NAFLD) describes abnormal accumulation of fat in liver cells

not caused by excessive alcohol consumption or another liver condition, such hepatitis

B or C.

The two types of NAFLD include nonalcoholic fatty liver (NAFL) and nonalcoholic steatohepatitis

(NASH).

These conditions differ in that there is no inflammation or liver cell damage with NAFL

but both are present with NASH.

Risk factors for NAFLD include type 2 diabetes, prediabetes, high blood pressure, overweight

or obesity, and abnormal blood fat levels.

Treatment centers primarily on lifestyle modification to improve underlying risk factors to reduce

the likelihood of developing liver scarring and cirrhosis.

Weight Reduction

Weight reduction is a cornerstone of NAFLD treatment.

A pooled analysis of 8 studies published in April 2012 in the journal Diabetologia reported

that just a 7 percent reduction in body weight resulted in decreased liver cell fat and liver

disease improvement.

The authors noted that improvements increased in parallel with the percentage of weight

reduction.

Reducing your caloric intake helps with NAFLD because it mobilizes the stored fat in your

liver cells.

In addition to liver disease improvements, weight reduction in these studies was associated

with improvements in markers for heart disease risk, such as levels of blood fats.

This is important because people with NAFLD are at increased risk for heart disease.

Approach

According to January 2018 practice guidance from the American Association for the Study

of Liver Diseases (AASLD), there is insufficient evidence to recommend a specific weight-reduction

diet for the treatment of NAFLD.

However, the guidance states that data suggest decreasing caloric intake by at least 30 percent

or by approximately 750 to 1,000 calories daily results in reduced liver cell fat.

Physical Activity

The AASLD guidance for NAFLD management states that the combination of a reduced-calorie

diet and moderate-intensity exercise provides the greatest opportunity for sustained weight

reduction.

This is likely because exercise helps increase your metabolic rate and burns calories.

There is also some evidence that excercise might reduce liver cell fat even with minimal

to no associated weight loss, as reported in a July 2012 Journal of Hepatology article.

Medications and Supplements

Pioglitazone

As of January 2018, AASLD guidance includes only one prescription medication for consideration

to specifically treat NASH.

Pioglitazone (Actos) was developed as a type 2 diabetes medication but has been shown to

improve liver inflammation and other indicators of liver damage in people with NASH.

AASLD states this medication may be used to treat biopsy-proven NASH in people with or

without type 2 diabetes after a discussion of potential risks and benefits.

Potential risks include weight gain and bone loss in women.

AASLD does not currently recommend pioglitazone for people with NAFL.

Vitamin E

An excess of free radicals -- chemicals that can lead to cellular injury when present in

abnormally high concentrations -- is thought to contribute to liver damage in people with

NASH.

Vitamin E is a potent antioxidant, a substance that neutralizes free radicals.

Other Considerations

As people with NAFLD usually have other health challenges and face an increased risk for

heart disease, the comprehensive medical treatment plan often includes other therapies.

This might include medications for diabetes, high blood pressure and/or blood fat abnormalities,

depending on individual circumstances.

Additionally, research is ongoing and treatment recommendations for NAFLD are likely to change

as new research data become available.

If you have any questions or concerns, talk with your healthcare provider.

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For more infomation >> Treatment for Fatty Infiltration of the Liver - Duration: 4:20.

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How To Removal Blackheads & Whiteheads On The Face Easy Acne Treatment On Face #376 - Duration: 7:22.

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Treatment for a common cause of blindness could be available in 5 years - Duration: 4:26.

Treatment for a common cause of blindness could be available in 5 years

by: David Williams

If you suffered from one of the most common forms of blindness, what would you give to

be able to cure it? That�s a question that might be up for discussion as a group of U.K.

researchers has reportedly developed a potential fix for one common cause of blindness. And

what�s more, it could be ready for public use within the next five years.

It is said that age-related macular degeneration (AMD), which ends up destroying a person�s

central vision, is one of the most common causes of blindness. But with the use of a

revolutionary stem cell therapy, the researchers were able to reverse its effects on at least

two different patients.

They did this through implanting a �patch� of stem cells over damaged areas at the back

of the eyes. As a result, the patients were able to not only read again but also see faces

that used to be nothing but blurry images on even fuzzier backgrounds. The solution

was crafted at the London Project to Cure Blindness, which is a collaboration between

experts from University College London (UCL) and Moorfields Eye Hospital.

According to Pete Coffey, a professor at UCL, the improvement in vision � which is usually

measured by way of lines on a reading chart � proved to be a lot better than they expected.

�We said we�d get three [out of the proposed 10] patients with vision recovery of three

lines. They probably wouldn�t get reading vision back,� he said. �The first patient

has got six lines improvement, which is astounding, and the second has five lines and he seems

to be getting better as the months go by.�

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What�s even more interesting is that they are both really reading, said Coffey. �At

best [the woman] could read about one word a minute with magnification. She is now reading

80 words a minute and [the man] is reading 50.� (Related: Stem cell therapy becoming

more widely accepted.)

�Wet� and �dry� macular degeneration The cure devised by the researchers was made

specifically for patients that suffered from the �wet� form of AMD, which is said to

be caused by sudden leakage from blood vessels in the eye that ends up destroying the macula,

a key component of the retina. Evidently, retinal pigment epithelial (RPE) cells that

can be found in the macula are highly important to the functioning of the light sensitive

photoreceptor cells in the eye, and they just die without the necessary RPE support.

Given the success of their latest trials, the researchers are now looking to test their

cure on at least one more patient in order to ensure that it is truly safe. If everything

goes well, Coffey thinks that an off-the-shelf version of their treatment could become available

for surgeons to use within the next five years. However, the cure will be limited for only

about the 10 percent of AMD patients which have the wet form of it. Dry AMD is more problematic

in that it develops slowly in comparison and can�t be cured. However, that could change

in the future, said Coffey.

According to Dr. Carmel Toomes, an associate professor at the Leeds Institute of Molecular

Medicine, the results of this research are quite promising. �These results give the

many patients out there who suffer from AMD and other retinal degenerations real hope

that stem cells replacement therapy may be a reality in the near future,� she said.

The fact that this early clinical trial has shown positive results means that a cure truly

could be quite close to becoming a reality.

For more infomation >> Treatment for a common cause of blindness could be available in 5 years - Duration: 4:26.

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Advanced and Future Treatments for Parkinson's - Duration: 3:12.

Advanced and future treatments for Parkinson's while there is no cure for Parkinson's disease

Recent research has led to improved treatments

Scientists and doctors are working together to find a treatment or prevention technique

Research is also seeking to understand who is more likely to develop the disease

in addition

Scientists are studying the genetic and environmental factors that increase the chance of a diagnosis

Here are the latest treatments for this progressive neurological disorder deep brain stimulation in

2002 the FDA approved deep brain stimulation

DBS as a treatment for Parkinson's disease

But advances in DBS were limited because only one company was approved to make the device used for the treatment in June

2015 the FDA approved the Brio neuro

Stimulation system this implantable device helped reduce symptoms by generating small electrical pulses throughout the body

gene therapy

Researchers haven't yet? Found a sure way to cure Parkinson's

Slow its progression or reverse the brain damage it causes

Gene therapy has the potential to do all three

Several studies have found that gene. Therapy can be a safe and effective treatment for Parkinson's disease

neuroprotective therapies aside from gene therapies

Researchers are also developing neuroprotective therapies

This type of therapy could help stop the progression of the disease and prevent symptoms from getting worse

Biomarkers doctors have few tools for evaluating the progression of Parkinson's disease

Staging while useful only monitors the progression of motor symptoms related to Parkinson's disease other

Grading scales exist but they're not used widely enough to be recommend as a general guideline

However, a promising area of research may make evaluating parkinson's disease easier and more exact

Researchers are hoping to discover a biomarker a cell or gene that will lead to more effective treatments neural transplantation

Repairing the brain cells lost from Parkinson's disease is a promising area of future treatment this procedure

Replaces diseased and dying brain cells with new cells that can grow and multiply

But neural transplantation research has had mixed results

Some patients have improved with the treatment while others have seen no improvement and even developed more complications

Until a cure for Parkinson's disease is discovered

Medications therapies and lifestyle changes can help those with the condition live a better life