Thứ Tư, 28 tháng 2, 2018

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Chagas Disease, also called American trypanosomiasis, is a parasitic disease common in Central and

South America, caused by a protozoan called Trypanosoma cruzi or T. cruzi for short.

T. cruzi is transmitted through the feces of the insect triatominae.

Triatominae is a type of reduviid bug also called the kissing bug because it typically

bites people on the face as they sleep at night - one heck of a good night kiss, huh?

The disease gets its name from Carlos Chagas, the physician who first described it.

The life cycle of T. cruzi starts with the epimastigote T. cruzi which sits in the lumen

of the Reduviid bug's midgut.

–Mastigote refers to the whip-like structure called a flagellum which protrudes from the

center of the T. cruzi and helps it move around.

While in the midgut, the epimastigote multiplies through binary fission.

Over time, the epimastigote transforms into a trypomastigote and at that point it loses

its ability to divide, but the trade-off is that it gains the ability to invade human

cells.

In fact "trypo" means to bore or punch into.

Reduviid bugs feed off the blood of humans, and they prefer biting a person's face,

which is why they're also called kissing bugs.

But unlike a normal kiss, the reduviid bug then defecates at the bite site, and if the

reduviid bug is infected with T. cruzi, the feces can contain trypomastigotes.

These trypomastigotes can then infect human skin cells at the bite location; or at mucous

membranes, particularly the conjunctiva of the eyes.

That can happen if a person unknowingly transfers the trypomastigotes by rubbing the bite site

on their face and then touching their eyes.

Once the trypomastigote invades a human cell, it transforms into an amastigote meaning that

it loses its flagellum.

The amastigotes multiply intracellularly, again through binary fission, and then transform

into blood trypomastigotes which can move through the blood and lymph to other tissues.

The blood trypomastigotes then invade more cells, and then again turn into amastigotes

to multiply intracellularly again - and that's how the cycle goes.

Now, a person infected by a T. cruzi infected reduviid bug, can then get bitten by a brand

new reduviid bug.

In that case, that reduviid bug might get infected by the trypomastigotes, and those

trypomastigotes would make their way into the reduviid bug's midgut and then differentiate

into epimastigotes - completing the life cycle.

Transmission from the reduviid bug to a person can also happen through infected organ and

blood donations, which is why blood screening is super important, and it can also spread

from mother to child during a pregnancy.

Now when a person is infected with Chagas disease, there's initially an incubation

period of up to two weeks.

During that incubation period, T. cruzi trypomastigotes invade host cells, amastigotes multiply, and

blood trypomastigote levels begin to increase in the blood.

Usually there's local inflammation as immune cells move towards the area of tissue damage.

When this happens at the bite site it's called a chagoma, and if it happens around

the eye, it can cause eyelid swelling which is called a Romaña's sign.

Further inflammation can also lead to meningoencephalitis, which is inflammation of the membranes covering

the brain and brain tissue, and hepatosplenomegaly, which is when the liver and spleen become

enlarged.

Trypomastigotes have a tendency to target certain tissues and cells - like smooth muscle,

cardiac muscle, and skeletal muscle, as well as neurons.

When those cells are damaged it can lead to problems like a pericardial effusion where

fluid collects around the heart which disrupts its function, or issues with the electrical

signals in the heart leading to heart block.

Generalized tissue damage can also lead to symptoms like fevers and fatigue.

The acute phase resolves when T. cruzi trypomastigotes are cleared from the blood, and over time,

antibodies against T. cruzi gradually decrease, indicating that the infection has been cleared.

However, in some individuals, that doesn't happen, and they go on to the chronic phase

of the infection.

In the chronic phase amastigotes linger in infected cells, and there are elevated levels

of T. cruzi antibodies even though trypomastigotes aren't usually in the blood.

The chronic phase can be asymptomatic, but some individuals develop progressive symptoms

from nerve and muscle damage.

The most notable symptom is cardiomyopathy, where the heart gets really large, which in

turn can cause arrhythmias like ventricular fibrillation and heart failure.

There can also be nerve damage; and gastrointestinal tract symptoms, like enlargement of the esophagus

and colon - called megaesophagus and megacolon.

The most definitive diagnosis for the acute phase is made by microscopic detection of

blood trypomastigotes in a blood smear or buffy coat preparation.

Polymerase chain reaction to detect T. cruzi DNA is also possible for certain sub-species,

even at very low levels in the blood.

But there's no "gold-standard" for diagnosing the chronic phase of the infection.

Some helpful tools are serology which identifies antibodies or molecular tests that look for

the presence of T. cruzi antibodies or antigens.

There's also xenodiagnosis which is when a reduviid bug's midgut is tested for T.

cruzi.

Finally, imaging like a chest X-ray to look at the size of the heart or a barium swallow

study to look for swelling of the colon can be helpful.

Finally, in the advanced stages, an electrocardiogram can be done to identify arrhythmias.

Treatment depends on the phase of the diseases.

The most effective way to resolve the acute phase beginning anti-parasitic medication,

like benznidazole or nifurtimox, early after infection and continuing for 2 to 4 months.

The chronic phase is mostly about managing the symptoms of cardiomyopathy, like with

pacemakers or anticoagulation medications, and treated cases of reactivation with anti-parasitic

medication.

A heart transplant may become necessary in advanced stages.

Alright, as a quick recap: Chagas disease is caused by an infectious parasite, Trypanosoma

cruzi that is most commonly transmitted through the feces of a reduviid bug after a bite.

In the acute phase, symptoms include inflammation and fever; and in the chronic phase there's

gastrointestinal disease

and cardiomyopathy.

For more infomation >> Chagas disease - causes, symptoms, diagnosis, treatment, pathology - Duration: 7:57.

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Customizing keto to help treat cancer - Duration: 0:58.

This is what my brain tumor looks like in 2013

and it's not a glioblastoma.

It actually in some ways is better and in some ways is worse

because it likes to travel through the spinal column

and spread to every organ in your body.

And I had brain surgery

and the oncologist and the neurologist were like, "This is awesome, we got most of it."

I'm like, "Most of it?"

And then they said, "Don't worry, go home, everything is going to be great."

I get on Dr. Google and I basically...

if I have chemo and radiation I have less than a year to live.

And I actually think that terminal malignant diagnosis was my best friend,

because I knew that if I did standard of care, and my doctors did not tell me this,

that I would die.

So here I am.

For more infomation >> Customizing keto to help treat cancer - Duration: 0:58.

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Piles Treatment-Permanent Cure of Piles at Home-Get 90% Relief in 1 Day - Duration: 2:13.

Namsate! I am Sachin Goyal and I welcome you to this program for public welfare.

Friends, If you are suffering from piles then follow this acupressure tip and home remedy to cure piles permanently.

Acupressure point for piles is located at the center between wrist joint and elbow joint.

You have to press this point with thumb, keep it pressed for 5 seconds and then release.

Press it 10-15 times.

Friends, when you press it you may find a painful area/spot. That is the acupressure point, you have to press it.

You may not be able to find exact point at once.

Press this whole center area and find out painful point which is right acupressure point.

You should press it on both hands.

You can press it 1 to 2 times a day.

You can press it at any time.

It gives instant relief in piles.

Pressing it daily cures piles very quickly.

Use this acupressure point to cure piles permanently.

Prepare home remedy for piles using carrot and spinach.

Take out 3/4 th glass of carrot juice.

Add 1/4 th glass of spinach juice to it and mix it well.

Add some black salt (rock salt) to it for taste.

Friends, carrot and spinach both are loaded with fiber which is necessary to keep digestion fit.

Also they keep abdomen cool.

The main cause of piles is high abdominal heat.

This home remedy helps to make digestion proper and balance the abdominal heat.

This two fold benefit of this remedy uproots and cures piles rapidly.

You should drink this 1 glass juice daily at any time.

It will give 90% relief in very first day.

When you continue it daily, it will cure piles within few days.

DON'T eat fried and spicy food because they make digestion improper and increase abdominal heat.

So avoid these things completely during home remedy course and also consume them less even after you cure piles.

You will get rid of piles permanently by this way.

Click Subscribe button below video to keep watching my acupressure tips, health tips and health facts.

Click above boxesTo Subscribe & Watch next videos

For more infomation >> Piles Treatment-Permanent Cure of Piles at Home-Get 90% Relief in 1 Day - Duration: 2:13.

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Diabetic Plant | Medicinal Plant for Diabetes Treatment - Duration: 8:03.

insolent plant for diabetes Kostas ligneous insulin plant is a medicinal

plant and capable of having magic cure for diabetes leaf of this horrible plant

helps to build up insulin by strengthening better cells of pancreas

in the human body this popularly known as insulin plant

the leaves of this horrible merciful plant are used to control blood sugar

levels or in treatment of diabetes the patient has to consume two leaves in the

morning and two leaves in the evening for first week from the second week one

leaf in the morning and one in the evening this dosage should be continued

for 30 days the leaves of insulin plant must be chilled well before swallowing

after chewing the leaves or leaf have a little water having natural

concentration of kuru silica acid insulin plant can have a positive effect

on blood sugar levels colic acid works and metabolism of glucose process like

insulin that reduces blood sugar levels by transporting glucose into cells and

out of the bloodstream this can be beneficial to anyone who has trouble

with high blood sugar levels and particularly to that in diabetes the

patients who are suffering from acute diabetes or advise to eat these leaves

by thoroughly chewing twice a day that is in the morning and in the evening to

control the blood sugar level diabetes is a disease of metabolism where body

not able to synthesis sufficient insulin or the blood cells stop responding to

the insulin produced in the body the leaves of insulin plant contain mostly

of kuru silicic acid which is beneficial and controlling diabetic the colic acid

present in the green leaves induces the insulin production and thus controls

hyperglycemia in the blood both Ayurvedic and allopathic

practitioners recommend the chewing the insulin leaves twice a day to bring the

blood sugar level totally under control if it is difficult to get the fresh

insulin leaves for the convenience of the patients the dried leaves powder is

also available commercially you can easily purchase it at any time add the

powder in the water boil it well and after cooling consume the water two

times a day in the morning before breakfast stomach a night before going

to bed to get the desired effect thus insulin plant is the cheapest way to

control which sugar level within the period of one month

generally insulin plant is known for its quality of controlling blood sugar level

but other than this plant has many other medicinal values the extract of the

plant are useful in treating many types of skin problems the leaves are used in

curing this is like fever asthma and even from cadiz the plant extracts are

very useful in enhancing the beauty of eyelashes the people especially kids who

are suffering from stomach worms are advised to consume the leaves or leaf

powder of the insulin plant all cleaves to treat diabetes and obesity our plants

are found everywhere in different species it beers bluish white flowers

with Ronnie fruits how our Cleaves can treat obesity and diabetes take two full

leaves of a plant from the opposite side which is little rough place it on your

feed soul and weird socks do the same with both the feet make sure that the

leaves are touching your soles completely allow the leaves to stay

there for whole day before going to sleep remove it and wash your legs

repeat the process with new leaves for a week after the week go for the blood

sugar checkup scientific base of using arc leaves for diabetes every curious

mind asks the question how it is good thing you must be getting curious to

know how actually oak leaves helps to lower blood glucose according to an

experiment done in rats they found that the leaves and the flowers were

effective to lower down serum glucose the administration of leaf and flower

extracts do step deserters in induced diabetes showed a significant reduction

in serum glucose levels it is concluded that chloroform extracts of Cala trapeze

began tea leaves and flus have significant anti-diabetic activity

precautions for oak leaves the milk hosing from our cleaves or poisonous

don't allow it to go inside your eyes otherwise it can damage your sight if

you were diabetic patient or fed up of unhealthy body then must give it a try

check it only well papaya leaves balance blood sugar based on the research

studies it was found that the phytonutrient compounds in papaya leaves

act in synergy to display a strong antioxidant and immune enhancing impact

in the bloodstream popping alkaloids and phenolic compounds are responsible for

their positive biological effects the nutrition inside the papaya leaf is

incredible diabetics have three good reasons to try papaya leaf extracts now

let us prepare papaya leaf tea for this we need papaya leaves and water take

about add some water add some papaya leaves

and allow it to boil for 10 minutes

benefits of papaya leaf tea enhances insulin sensitivity poor insulin

sensitivity is the cause for type 2 diabetes which causes inefficient

glucose uptake by the cells a study on Meridian population showed that papaya

leaf extract supplementation decreased the enzyme levels of alt and ast by

omakr soft type 2 diabetes among diabetic patients and improve insulin

sensitivity decreases diabetes complications the mix of antioxidants in

papaya leaf extracts are helpful in decreasing the secondary complications

of diabetes such as fatty liver kidney damage and oxidative stress accelerates

own healing the process of own healing is delayed or hindered in a debate

patient and can cause other complications many studies have

confirmed that consuming papaya leaves enhanced the process of old healing due

to its antibacterial and remarkable antioxidant action the health benefits

extend beyond blood sugar stabilization some clinical studies have confirmed

that the papaya leaf extracts effectively inhibit cancer cell growth

and improve immune activity the best way to consume the papaya leaves is in the

form of tea prepare a tea infusion by adding 10 leaves to half a liter water

now take this water into your glass allow it to boil till the quantity of

water is decreased to half cool and consume in small doses as needed to

treat into addition for detoxifying for immune building purposes or as a gentle

tonic by taking this tree regularly you can maintain stable blood sugar levels

for any queries and suggestions feel free to comment in below comment box

thanks for watching this video for more videos like us and subscribe to get

latest updates and notifications click on Bell button

For more infomation >> Diabetic Plant | Medicinal Plant for Diabetes Treatment - Duration: 8:03.

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U.S. Naval, Japanese medical professionals share treatment methods - Duration: 1:45.

With the growth of Marine Corps Air Station Iwakuni, available staff and resources for

healthcare are limited until the new Robert M. Casey Medical and Dental Clinic opens this summer.

Until then, base residents rely on the host nation's medical care for treatment and support.

Naval medical officers joined local Japanese medical specialists for this year's Joint

Medical Symposium, Feb. 23, to collaborate treatment plans and healthcare ideas.

Col. Richard Fuerst, commanding officer of MCAS Iwakuni, spoke to guests at the event.

"I'm looking forward to improving everything that we are able to do primarily from an administrative

point of view so that we all understand what the rules are and that we're not taking

advantage of you and that our patients aren't taking advantage of you and that we're better

neighbors in Iwakuni City and the surrounding areas.

So, I'm very interested in that and we're going to work hard to improve the situation."

The symposium allows Naval and Japanese professionals a chance to network with

like-minded individuals to help build a stronger medical community for the air station.

Lt. Sara Brubaker, a Naval Doctor of Physical Therapy, presented during the symposium.

"So with this medical symposium the keynote speakers were myself and one of the orthopedic

surgeons from Iwakuni Care Clinic and so we discussed different types of patients that

the orthopedic surgeon sees and then how physical therapists would work with those patients as well."

This year, twenty-two guests from MCAS Iwakuni and thirty-nine Japanese guests attended the symposium.

Reporting from Iwakuni, Japan, I'm Marine Sgt. Sara Abrego.

For more infomation >> U.S. Naval, Japanese medical professionals share treatment methods - Duration: 1:45.

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Rejuvalex Hair Growth Treatment - Rejuvalex Phone Number - Duration: 1:22.

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For more infomation >> Rejuvalex Hair Growth Treatment - Rejuvalex Phone Number - Duration: 1:22.

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Woman in Omaha for Leukemia treatment has truck stolen - Duration: 2:22.

For more infomation >> Woman in Omaha for Leukemia treatment has truck stolen - Duration: 2:22.

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Onslow Co. works to battle the opioid crisis with new treatment center - Duration: 4:04.

For more infomation >> Onslow Co. works to battle the opioid crisis with new treatment center - Duration: 4:04.

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Rejuvalex Scam - Rejuvalex Hair Growth Treatment - Duration: 1:26.

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